Neuropeptides 55, 99109
EVs derived from follicular fluid target the inhibition of the 10th chromosome homologous deletion phosphatase and tensin homolog deleted on chro-mosome ten (PTEN), via miR-18b-5p, thereby activating AKT to open the PI3K signaling pathway and promote steroid synthesis (Zhou Z
The neuroprotective efficacy of phytochemicals in maintaining brain health during aging is primarily attributed to multiple mechanisms, including AChE and MAO inhibition, antioxidative and anti-inflammatory activities, antithrombotic and anti-apoptotic properties, and the enhancement of neurotrophic signaling pathways (8)
However, more human research is needed to fully understand its effects on fat metabolism and long-term weight balance
J Pineal Res 32:179186 Gomez-Pinilla PJ, Camello-Almaraz C, Moreno R, Camello PJ, Pozo MJ (2006) Melatonin treatment reverts age-related changes in guinea pig gallbladder neuromuscular transmission and contractility
